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John MacNeil Obituary (2022) - Hamilton, ON - The Hamilton Spectator

Legacy.com
John Hector MacNeil, Dearly loved husband of Jean for 64 years, their love for each other was so special; amazing dad to Elaine Horvat (Ivan), Raymond MacNeil...
30 months ago

Fast Lithium Ion Conduction in Li2SnS3: Synthesis, Physicochemical Characterization, and Electronic Structure

ACS Publications
Li 2 SnS 3 is a fast Li + ion conductor that exhibits high thermal stability (mp ∼750 °C) as well as environmental stability under ambient conditions.
119 months ago

Selective Inhibition of Orexin-2 Receptors Prevents Stress-Induced ACTH Release in Mice

Frontiers
Orexins peptides exert a prominent role in arousal-related processes including stress responding, by activating orexin-1 (OX1R) and orexin-2 (OX2R)...
4 months ago

Ionic Mechanisms Underlying the Excitatory Effect of Orexin on Rat Subthalamic Nucleus Neurons

Frontiers
Central orexinergic system deficiency results in cataplexy, a motor deficit characterized with a sudden loss of muscle tone, highlighting a direct...
5 months ago

Development of tissue-engineered models of oral dysplasia and early invasive oral squamous cell carcinoma

Nature
Here we describe a three-dimensional in vitro model of the oral epithelium that replicates tumour progression from dysplasia to an invasive phenotype.
157 months ago

Spatial mRNA expression patterns of orexin receptors in the dorsal hippocampus

Nature
Orexins are wake-promoting neuropeptides that originate from hypothalamic neurons projecting to widespread brain areas throughout the...
1 month ago

Orexin neurons mediate temptation-resistant voluntary exercise

Nature
Despite the well-known health benefits of physical activity, many people underexercise; what drives the prioritization of exercise over...
3 months ago

Orexin 2 receptor (OX2R) protein distribution measured by autoradiography using radiolabeled OX2R-selective antagonist EMPA in rodent brain and peripheral tissues

Nature
OX2R protein distribution in rats was comprehensively assessed in 51 brain regions and 10 peripheral tissues using in vitro autoradiography with [ 3 H]-EMPA.
30 months ago

Hypothalamic orexins as possible therapeutic agents in threat and spatial memory disorders

Frontiers
Orexin-A and orexin-B, neuropeptides produced exclusively in the lateral hypothalamus, have been implicated in various functions, including memory.
16 months ago

Exaggerated postnatal surge of orexin neurons and the effects of elimination of excess orexin on blood pressure and exaggerated chemoreflex in spontaneously hypertensive rats

Frontiers
An overactive orexin (OX) system is associated with neurogenic hypertension and an exaggerated chemoreflex in spontaneously hypertensive rats (SHRs).
2 months ago