Shelly-Ann Fraser, the Olympic and world 100 metres champion, has been handed a six-month drug ban by the International Association of Athletics Federations.
The 23-year-old Jamaican tested positive for oxycodone at the Diamond League meeting in Shanghai in May, but said the result was because of medication she took for toothache.
She was provisionally suspended back in June and the IAAF has now confirmed she will not be allowed to return to action until 7 January.
Oxycodone is banned as a narcotic but is not considered performance enhancing or to be a masking agent. Fraser was the eighth Jamaican athlete to test positive in the space of a year.
Bruce James, president of her MVP Track and Field Club, said at the time: "She took pain medication after a dental procedure which is not a performance enhancement drug.
"We are withdrawing her from all competitions until we are able to have a hearing to determine what sanction will apply, or if she will be exonerated.
"The IAAF had advised us that the offending substance is oxycodone. Google it. It is not a performance-enhancing drug."
Fraser won the 100m title in Beijing in 2008 before claiming the world title as well as relay gold in Berlin the following year.